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FFPE

Formalin-Fixed Paraffin-Embedded Samples (FFPE)

The fixation of human tissues with formalin, and their subsequent embedding in paraffin, has been a routine method of preserving surgical samples for many years.  But these extensive resources are rarely used in microarray-based gene expression or chromosome alteration studies, because nucleic acids isolated from FFPE sources are typically degraded.

Expression Analysis has partnered with NuGEN Technologies to optimize their WT-Ovation™ FFPE System.  This whole transcriptome amplification solution uses NuGEN’s proprietary Ribo-SPIA™ technology to generate biotin-labeled hybridization targets from small and degraded RNA samples that perform well in microarray expression profiling studies.