Expression Analysis offers Luminex’s patented xMAP liquid bead system for multiplexing from 1 to 100 targets per sample and profiling up to 1000 samples per day. Because of xMAP’s robust multiplexing, xMAP can deliver more data in less time with high reproducibility and format flexibility. xMAP® technology from Luminex is based on microspheres that are internally dyed with two spectrally distinct fluorochomes. By changing the relative amounts of the two dyes, one hundred unique sets of microsphere beads are generated that can be spectrally distinguished. Different oligonucleotides can be linked to different microsphere sets and then combined for multiplex assays. The oligo-coupled beads are hybridized to labeled RNA samples for expression profiling or DNA targets for genotyping. A third fluorochrome coupled to the RNA or DNA target quantifies the degree of hybridization at the microsphere surface.